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Of note, CD38 possesses a low K m value for NAD + in the range of 1525 M [63, 64]

51 Reduced energy for metabolic activity within brain cells leads to their diminished ability to engage in normal neuronal activities, including maintenance of cell membranes and production of myelin, 13 as well as activities related to learning, memory, and cognition

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Fifth, inter-individual differences in the levels of endogenous antioxidants may affect responses to antioxidant therapy [139]