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L.F., Z.Y., S.Z., Y.Z., J.Z., L.X., M.M., J.F
Ames mice maintained a nearly 1:1 (0.94) ratio of SAM to SAH on MET restriction, whereas in wild-type mice, this ratio was 1.49 (Figure 2)
(PubMed) Chen W, Qi J, Feng F, et al
However, cortical neurons that also depend much stronger on IIS than on Bdnf-signalling for their survival also activate the PI3K-pAkt branch [117], but LY294002 does not completely attribute for survival upon IIS
