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L-carnitine helps mitigate the harmful effects of non-esterified fatty acids (NEFAs) during the follicular phase and oocyte maturation, optimizing mitochondrial function and reducing lipid toxicity and oxidative stress ( L-carnitine is acquired both internally and externally

Additionally, the expression levels of nf-b and il-1 were remarkably upregulated in the gut and liver of fish fed HFD 19

Food Chem 135:14401447

Allosteric regulation Regulation of protein activity by the binding of an effector molecule to an allosteric site (a position that is not the active site), which often leads to a conformational change that affects the function of the protein