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The actual cost depends on the supplier, the duration of the experiment, and the dose being administered to test subjects
In addition, low levels of CAT activity were observed in NASH patients, suggesting a reduced scavenging capacity of the antioxidant system

The primarily affected organ is the liver, and patients suffer from bile duct proliferation, centrilobular necrosis, hepatic lesions, and fatty acid infiltration, which often ends in liver cancer (Wu and Santella, 2012