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[DOI] [PubMed] [Google Scholar] 5.Caputo T, Gilardi F, Desvergne B

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Current PH therapies that include endothelin-1 (ET1) receptor antagonists, prostacyclin analogs, cGMP- phosphodiesterase (PDE) inhibitors, and Ca 2+ channel blockers impede, but do not stop the disease process, emphasizing the need for a finding of alternate treatments [2]
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