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Description
The landmark Phase IIb clinical trial published in The Lancet (TIPO-1 study) evaluated 203 obese patients randomly assigned to receive tesofensine at doses of 0.25mg, 0.5mg, or 1.0mg daily for 24 weeks alongside an energy-restricted diet
The BCL2L1 and PGAM5 axis defines hypoxia-induced receptor-mediated mitophagy
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