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Food Chem Toxicol 48(1):298305 Kant K, Walia M, Agnihotri VK, Pathania V, Singh B (2013) Evaluation of antioxidant activity of Picrorhiza kurroa (leaves) extracts

12.1 Curcumin and anticoagulants Curcumin, the bioactive component of turmeric, has demonstrated antiplatelet and anticoagulant properties in numerous studies
These patterns suggest that microbial interactions exhibit hierarchical organization, with increasing specificity at lower taxonomic levels

And the thought is that the muscles are going to take first dibs and you need to have a high dose to get it to the brain