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Histological analysis showed a small but significant increase in 4HNE-positive cells in the Auranofin and combination groups (Fig
Mutat Res Mol Mech Mutagen 482(12):2126

however, the mechanism remains unclear and requires further study

The regulation of programmed cell death (PCD) is a crucial determinant of cell fate (127), and studies have demonstrated that copper overload can induce various forms of PCD in cells
