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J Hazard Mater 250:318332
VCN is mainly an inhibitor of the phosphodiesterase-1 enzyme (the enzyme responsible for the degradation of cGMP and cAMP), with a high affinity towards (PDE1A/1B) isozymes 25
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221 Other compounds have been reported as NOX inhibitors with limited or not completely investigated isoform selectivity ( 11 19 , Figure 8)
