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The current experimental data indicate glucocorticoids have direct effects on the endothelium, and depending on the context these effects may be beneficial (e.g., infection) or detrimental (e.g., hypertension associated with chronically elevated levels of glucocorticoids)

Bevacizumab in combination with oxaliplatin-based chemotherapy as first-line therapy in metastatic colorectal cancer: A randomized phase III study
