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2 Unlike other types of cell death, such as apoptosis, necrosis, and autophagy, ferroptosis is an iron-dependent form of regulated cell death characterized by impaired mitochondrial morphology, iron overload, disturbed lipid peroxidation, and excessive oxidative stress

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The physicochemical characteristics of ibuprofen hinder its brain delivery

The increase in Glu concentration is potentially driven by the increased demand for glutamine during keratinocyte hyperproliferation, rapid protein synthesis and enhanced immune cells activity that are characteristic to PS 6,16,17