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This function, often called the Windkessel effect, helps smooth the pulsatile force generated by each heartbeat and protects the smaller vessels of the brain, kidneys, and other organs

CRH is part of a family of neuropeptides together with the urocortins 1, 2 and 3 (52)

(PubMed) da Costa KA, Corbin KD, Niculescu MD, Galanko JA, Zeisel SH
The most clinically significant interaction concern involves antidiabetic medicines
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