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182 In addition, d-penicillamine has been shown to inhibit the activity of LOX, thereby resulting in impaired collagen cross-link formation, reduced VEGF expression, and delay the progression of glioblastoma in vivo

For instance, it was observed that mmachc shares 51% sequence identity with the human protein but differs at the C-terminus, resulting in a shorter protein (250 amino acids in zebrafish versus 282 amino acids in humans)