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Description
The reducing power of DTT is limited to pH values above 7, since only the negatively charged thiolate form -S is reactive (the protonated thiol form -SH is not)
Glutathione could prevent this phenomenon, but its concentration decreases during aging
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Since it occurs as a result of cell turnover and movement of deeper clogs to the surface, purging should last for about one complete skin cycle, which is about 28-40 days or four to six weeks
