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75,76 ASOs that employ this mechanism are splicing-switching oligonucleotides, which modulate functional target gene expression by skipping or including exons

doi: 10.1146/annurev.nu.04.070184.002513

Lipid nanoparticles (LNP) with mRNAs were injected into the tail vein of model animals at postoperative 7 and 14 days after tracheal administration of bleomycin