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If this period does not improve liver function and/or decrease episodes of decompensation, a liver transplant can be considered
Moreover, they found no significant correlation between TMAO and mitochondrial DNA copy number
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The proposed pathomechanisms include the hyperglycemia-induced elevated sorbitol and glucosamine pathway, dysregulated glycolysis, and mitochondrial oxidative phosphorylation in diabetic nerve tissues leading to mitochondrial dysfunction and oxidative stress [46]
