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Other than that, its very important for the proper function of our brain

Dosage adjustments may be warranted based on factors such as age, renal function, and concomitant medications

Consequently, the forms of polyphenols present in human blood and tissues differ from those in foods, complicating the identification of all metabolites and the assessment of their biological activity

This is often due to increased osteoclastic activity and diminished osteoblast activity, as observed in age-related and secondary osteoporosis or in inflammation-induced (e.g., in rheumatoid arthritis) or cancer-induced bone loss (reviewed in [2])