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Furthermore, significant accumulation of TZ in the brain following administration indicates its ability to cross the bloodbrain barrier, highlighting its considerable promise for PD treatment [183]

ALDHs have the capacity to influence neural function, particularly in dopaminergic nerves

Indeed, recent studies have shown that HIF-2 can be targeted by selective inhibitors and have indicated that these molecules effectively suppress cancer cell growth and tumor angiogenesis characteristics in ccRCC 79,80,81,82
