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Luminescence was recorded for 45 min at 1 min intervals using a Fluoroskan Ascent FL (Thermo Scientific, Rockford, IL, USA) fluorimeter (excitation: 538 nm, emission: 604 nm), and the slopes were used for calculations
Importantly, MAA adducts can induce inflammatory processes in stellate and endothelial cells of the liver

Despite these advancements, several challenges persist, especially rapid mucociliary clearance in the nasal cavity and poor patient adherence, which limit clinical usage of intranasal medications

This creates inconsistent dosing from injection to injection, which makes it impossible to properly titrate or adjust your protocol