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In addition, many flavonoids exert actions on different molecular pathways related to glycaemia but also exert antioxidant, anti-glycaemic, and anti-inflammatory actions, making them bioactive compounds of interest in the management and prevention of metabolic complications related to hyperglycaemia

These actions do not depend on insulin and thus leptin signaling is being actively investigated as an alternative means by which diabetes might be treated

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In fact, OSBP is one of several such proteins, including OSBP9 and GRAMD1s/Asters (GRAMD1a/GRAMD1b/GRAMD1c)