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These factors, including vWF (von Willebrand factor), ADAMTS13, aPTT, FVIII, FXI, FVII, FX, ETP, PAI-1, protein C, and plasmin, were grouped by their roles in platelet adhesion, intrinsic and extrinsic pathways, common pathways, and fibrin dissociation

Circ Res 102(4):401414 Karwi QG, Sun Q, Lopaschuk GD (2021) The contribution of cardiac fatty acid oxidation to diabetic cardiomyopathy severity

While the numbers are startling, researchers are conducting studies to understand why the trend appears to lean toward one sex, especially as one in five Americans is at risk of developing an autoimmune disease at some point in their lives