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Like most neural elements, the RPE cells are mitotically dormant in vivo and, because of their many functional responsibilities, they are metabolically highly active, using mitochondrial oxidative phosphorylation (OXPHOS) as their major energy source (24)
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Riessland M, Ximerakis M, Jarjour AA et al (2024) Therapeutic targeting of senescent cells in the CNS
Therefore, maintaining healthy levels of SAMe and glutathione is crucial for optimal liver function and effective detoxification
