glutathione journal What is Glutathione? – HealthMatters: The Frontiers | Glutathione: Pharmacological aspects

Nat Rev Endocrinol (2012) 8:74354

is not extremely dangerous on its own, its reaction with NO (formed during the translation of L-arginine to L-citrulline) produces the powerful oxidant, peroxynitrite (ONOO - ), which contributes to neuropathological changes by nitrating tyrosine (Peluffo et al., 2004)

Given that glutamate is the major excitatory neurotransmitter in the central nervous system and NMDARs play critical roles in synaptic activity, it is not surprising that maladaptive NMDAR signaling is implicated in a broad range of neuropsychiatric, neurodevelopmental, and neurodegenerative disorders [6]

VEGF helps stimulate the growth of new blood vessels