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These data suggest that targeting serotonin and norepinephrine may represent an efficient strategy in treating painful CIPN

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SFs ability to activate the Nrf2 signaling pathway and associated antioxidant enzymes NQO1, HO-1, and GPx positions it as a promising therapeutic agent for mitigating these damaging effects [33]

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To graphically visualize dose-response associations and assess log-linearity, we fitted Cox models with restricted cubic splines (3 knots)

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AMP-activated protein kinase regulates lymphocyte responses to metabolic stress but is largely dispensable for immune cell development and function

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