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Its a two-way street in IBD, with the gut microbiome changes potentially causing high homocysteine, but then high homocysteine will increase the inflammation in the gut.[ref] Gastrointestinal production of homocysteine: Gut microbes that produce folate: The amount of folate produced by the gut microbiome is on a similar scale to what we get from food, so it is a significant source of folate for most people

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[DOI] [PMC free article] [PubMed] [Google Scholar] 10.Bieganski T., Kusche J., Lorenz W., Hesterberg R., Stahlknecht C.D., Feussner K.D

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