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Alterations in gut bacteria are associated with ASD symptoms, and SFN has been shown to increase beneficial bacterial taxa, such as Lactobacillus and Prevotella

Mass spectrometry-based analyses confirmed that BPTES-treated adipocytes displayed reduced glutamine conversion (determined as 13 C-glutamine incorporation) and increased intracellular levels of multiple glycolytic metabolites, ETC protein levels, OCR and ECAR (Extended Data Fig

Ethoxyresorufin O-deethylase and methoxyresorufin O-demethylase activities were measured in the same way as described for the pentoxyresorufin assay, except that the concentration of substrates was 1.7 mM ethoxyresorufin and 5 mM methoxyresorufin assays were carried out using the microsomal fraction of the tissue ( 2.22 Statistical analysis Data were evaluated by ShapiroWilk tests to confirm normality of distribution and by Grubbs test to identify outliers