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[DOI] [PMC free article] [PubMed] [Google Scholar] 77.Kawahara B., Ramadoss S., Chaudhuri G., Janzen C., Sen S., Mascharak P.K

Tissues with a high demand for ATP are most affected, with the nervous system being particularly vulnerable because of its predominate reliance on carbohydrate metabolism for ATP generation

Since we know cramps are primarily about neuromuscular fatigue, prevention looks like this: Training specificity matters most
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