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Most of these cases were classified as mild and self-limiting, meaning they resolved on their own without treatment

Calamaras TD, Lee C, Lan F, Ido Y, Siwik DA, Colucci WS

J Neurochem 104 , 10911100, (2008)

However, despite the growing consensus on their clinical relevance, the precise definition and identification of CSCs remain subjects of ongoing debate
