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Although NO production was enhanced considerably in Long COVID, nitrotyrosine levels were not altered, although increased nitrotyrosine indicates an increase in reactive nitrogen species with increased NO2 binding to tyrosine, thereby forming an immunogenic neoepitope [89]

Clinical observations of patients have indicated that long-term exposure to high doses of propofol (surpassing 45 mgkg 1 h 1 and lasting over 48 h) can induce propofol infusion syndrome (PRIS) by damaging mitochondrial complexes II and IV in the muscles [30]

doi: 10.1097/00075200-200203000-00019 137 KorleyF

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