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Description
DHFR is also required to convert folic acid to DHF
Sattar N, McGuire DK, Pavo I et al (2022) Tirzepatide cardiovascular event risk assessment: a pre-specified meta-analysis
Genome-wide association studies and clinical investigations have established a link between the MTHFR C677T polymorphism and a heightened susceptibility to hypertension and hypertension in pregnancy, with a potential increase in risk of up to 87% [98]
Key takeaways: The MTHFR enzyme converts folate (vitamin B9) to its active form, 5-MTHF
