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Rapid proliferation requires the massive synthesis of new proteins, nucleic acids (RNA and DNA), and phospholipids, and the synthesis and modification processes of these substances also require the support of methylation reactions (35)

SS-31 (Elamipretide) is a synthetic mitochondria-targeting tetrapeptide designed to penetrate cell membranes and selectively accumulate in the inner mitochondrial membrane

Moreover, activated CD4 + T cells in patients with RRMS exhibited increased expression of the GLUT1 protein at the plasma membrane