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Antibodies like all polypeptides have an Isoelectric Point (pI), which is generally defined as the pH at which a polypeptide carries no net charge

doi: 10.3389/fpsyt.2019.00892

Sorbitol is prone to accumulate in kidney cells causing permeability alteration, cell swelling and rupture, which ultimately aggravate mesangial cells hypertrophy, glomerulosclerosis and tubulointerstitial fibrosis (Shen and Wang, 2021)

Liu J-Q, Zhao M, Zhang Z, Cui L-Y, Zhou X, Zhang W, et al
