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GSH was well-tolerated and did not produce unexpected toxicity
8 Reduced GSH occurs in millimolar concentrations intracellularly in humans, but in only trace amounts in plasma and most other body fluids
The glutaredoxin and thioredoxin systems In mammalian cells, the cytosolic and mitochondrial thioredoxin systems and the glutathione-glutaredoxin system have a key role in antioxidant defence and have a great impact on the cellular redox state (Lu and Holmgren, 2014)
Julien B Cloning and Heterologous Expression of the Epothilone Gene Cluster
