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Open Biol 14:240035
Heres the honest side-by-side
Most people tolerate B12 well, even at high doses, as excess amounts are excreted through urine
Certain populations face higher deficiency risk: vegetarians and vegans (B12 is primarily found in animal products), adults over 50 (decreased stomach acid reduces B12 absorption), individuals with digestive disorders like Crohn's disease or celiac disease, and those taking medications like metformin or proton pump inhibitors
