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Numerous studies have also shown how important the portal glucose sensor is in maintaining glucose homeostasis and how GLP- 1 receptors are related to portal glucose sensing, with GLP- 1 being required for portal glucose to trigger the insulin response

The primary objective of this review is to present a comprehensive insight of the effect of metal ions, particularly zinc, in modulating -synuclein aggregation, fibrillation and resultant toxicity analyses along with the technological and scientific challenges involved therein

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