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Jekyll and Mr

A mechanism for glutamate toxicity in the C6 glioma cells involving inhibition of cysteine uptake leading to glutathione depletion

M., Tietze, F

Interestingly, the crystal structure of the SOCS2Elongin B/C complex revealed that the C-terminus of the SOCS box and the N-terminus of the extended SH2 subdomain (ESS) can interact and maintain the stability of the SH2SOCS box domain interaction (131)