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Review about each risk of bias item for each included study

However, the study did not directly measure the association between TMAO and H 2 S, hence, the direct impact of TMAO on H 2 S production and its vascular effects warrants further investigation

Vitamin E, known for its established antioxidant roles, has been evaluated for cancer prevention

Koeller DM et al (2002) Biochemical, pathologic and behavioral analysis of a mouse model of glutaric acidemia type I
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