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Before discussing the experimental and therapeutic cerebellar stimulation techniques that have been employed in human conditions and animal models, we first revisit the basic anatomical structure, connectivity, and function of the mammalian cerebellum in order to fully appreciate the outcomes of its stimulation in health and disease
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After IM injection, the onset of analgesia occurs in about 30 minutes, with a peak effect around 1 to 2 hours, and a duration of action of 4 to 6 hours
