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Urolithin A, a natural compound, can promote mitophagy and improve mitochondrial function and reduce oxidative stress in aging-related diseases [520]

Results from the PIVENS trial showed that oral administration of the anti-oxidant vitamin E improved liver dysfunction and the pathological conditions of NASH [17]

Oxidative glutamate toxicity involves mitochondrial dysfunction and perturbation of intracellular Ca2+ homeostasis

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