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Description
Sickling provoked by hypertonicity in the renal medulla causes damage that eventually leads to hyposthenuria (the inability to concentrate urine), which increases the propensity for dehydration and its attendant risks
One cannot, however, exclude low levels of Glut9 expression in the proximal tubule that are not detected by immunofluorescence microscopy, because Glut9a mRNA is observed in this tubule segment (90)
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