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One major resveratrol derivative is resveratrol-3- O --glucoside, also called piceid ( Figure 1 ) (3)

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A broad spectrum of interventions for ME/CFS has been investigated, encompassing pharmacological options such as rituximab, rapamycin, and lumbrokinase, as well as non-pharmacological approaches including yoga, CBT, and acupuncture

The very different substrate preference for these enzymes, however, suggests that the mEH is largely responsible for metabolism of reactive epoxides on cyclic backbones, with the sEH showing a high preference for EpFA