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The adjacent keratinocytes are usually hyperpigmented, and a slight degree of epidermal rete hyperplasia may be present
The regenerative effect of PRP is deemed to be exerted through the high concentrations of platelets containing several growth factors including VEGF, EGF, IGF-1, PDGF and FGF [511]
Despite the success of the metabolic labeling strategy, precise mapping of glycans to nanoscale cellular or anatomical features remains difficult due to the added challenge imposed by the diffraction of light, which limits resolution on optical microscopes to approximately 200 nm
