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doi: 10.3389/fonc.2025.1582116 Received 24 February 2025 Accepted 30 April 2025 Published 04 June 2025 Volume 15 - 2025 Edited by Alvaro Marn Hernndez, Instituto Nacional de Cardiologa, Mexico Reviewed by Bjrn Steen Sklhegg, University of Oslo, Norway Yasuhiro Saito, Keio University, Japan Updates Copyright 2025 Ge, Xu, Cui, Huang, Liu and Yin