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Values are means standard deviations

Neuroglial changes in physiological brain ageing are relatively subtle, with white matter being the most affected: in healthy old age, white matter volume is decreased by ~ 10%, whereas the grey matter is reduced by a mere 3%

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During the catalytic cycle of GPX4, the active selenol (-SeH) is oxidized by peroxides to selenenic acid (-SeOH), which is then reduced with glutathione (GSH) to an intermediate selenodisulfide (-Se-SG)
