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Chronic stress can deplete glutamine stores, making the gut more vulnerable to damage

Krause 2007

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Of note, CTP:phosphocholine cytidylyltransferase (CCT), the rate-determining enzyme in de novo synthesis of PC, was less expressed in IECs from Apc +/Min /Stard7 IEC mice, possibly as a result of PC accumulation in the ER due to a defective transfer to mitochondria (Fig
