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doi: 10.1007/s00281-022-00940-w 69 AbeKTakahashiAFujitaMImaizumiHHayashiMOkaiKet al

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The mean study age was 58.4 7.4 years, mean was 32.1 5.1 kg/m 2 , HbA1c 8.66 0.92% [43]

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Long-term risks (over 6 months excessive use): microinflammation in renal tubules, increased uric acid, and disturbed methylation balance (SAM/SAH ratio) due to excess creatine recycling

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Mehlem A, Palombo I, Wang X, Hagberg CE, Eriksson U, Falkevall A

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