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Furthermore, the incidence of metabolic disorders affecting tissues such as the liver, heart, and skeletal muscles that solely depend on FAO for metabolism has been reported [33]

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It was previously approved by the FDA for diagnostic evaluation and treatment of pediatric GH deficiency and is now widely used off-label in research and clinical settings to address adult-onset GH insufficiency and age-related hormonal decline

HGH reduces insulin sensitivity and can raise blood glucose, potentially leading to insulin resistance with chronic use