glutathione content in borrelia Lyme Disease Pathogenesis New insights into Lyme disease

Dieter SM, Ball CR, Hoffmann CM, Nowrouzi A, Herbst F, Zavidij O, et al

Ribonucleosides (adenosine, guanosine, inosine) are first degraded to their respective bases (adenine, guanine, hypoxanthine) by purine nucleoside phosphorylase (PNP), then salvaged to NMPs via PRPP-dependent enzymes adenine phosphoribosyltransferase (APRT) and hypoxanthineguanine phosphoribosyltransferase (HGPRT) [37, 38]

The mitochondrial electron transport chain (ETC) and NADPH oxidase (NOX) are key sources of ROS in -cells, and their dysfunction further promotes oxidative stress

Sleep inducing DSIP Insomnia and sleep disorders For those lost in the shadows of sleepless nights, DSIP may offer relief for patients suffering with insomnia