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Skin hyperpigmentation in B12 deficiency was most commonly observed on the hands and feet (dorsal aspect), with the knuckles being the most prominent site
Instead of a simple side-chain modification, cysteine residues can form disulfide bonds with each other
Ascertaining the behavior of these structures over time is of interest because the results will lead to better understanding of the rapid disease relapse process in tumors and corneal neovascularization following the cessation of treatment
