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67 This increased demand reflects the need to reprocess and reinterpret sensory information, often relying on other sensory modalities such as cutaneous (skin) or visual inputs to compensate for disrupted proprioceptive feedback

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IL-1 inhibits the activation of the TrkB receptor and disrupts its associated downstream signaling pathways such as PLC1 and the MAPK pathway, though it does not significantly affect TrkB expression
